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1

Latent inhibitors part 11. The synthesis of 5-spirocyclopropyl dihydroorotic acid

Stephen Husbands, William Fraser, Colin J. Suckling, Hamish C.S. Wood

Journal:

Year:

1995

Language:

english

File:

PDF, 356 KB

english, 1995

2

Tetramic acid and imidazolidinone syntheses via unexpected base induced cyclisations of alanine derived Weinreb amides

Colin L. Gibson, Alan R. Kennedy, Raghavendar R. Morthala, John A. Parkinson, Colin J. Suckling

Journal:

Year:

2008

Language:

english

File:

PDF, 483 KB

english, 2008

3

Distamycin Analogues with Enhanced Lipophilicity: Synthesis and Antimicrobial Activity

Khalaf, Abedawn I., Waigh, Roger D., Drummond, Allan J., Pringle, Breffni, McGroarty, Ian, Skellern, Graham G., Suckling, Colin J.

Journal:

Journal of Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 275 KB

english, 2004

4

In Silico Footprinting of Ligands Binding to the Minor Groove of DNA

Anthony, Nahoum G., Huchet, Guillaume, Johnston, Blair F., Parkinson, John A., Suckling, Colin J., Waigh, Roger D., Mackay, Simon P.

Journal:

Journal of Chemical Information and Modeling

Year:

2005

Language:

english

File:

PDF, 1008 KB

english, 2005

5

Specific inhibitors in vitamin biosynthesis. Part 10. Synthesis of 7- and 8-substituted 7-deazaguanines

Gibson, Colin L., Ohta, Kyuji, Paulini, Klaus, Suckling, Colin J.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1998

Language:

english

File:

PDF, 227 KB

english, 1998

6

Latent inhibition of liver alcohol dehydrogenase by a substituted allyl alcohol

Schorstein, David, Suckling, Colin J., Wrigglesworth, Roger

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1978

Language:

english

File:

PDF, 169 KB

english, 1978

7

Reactive intermediates in enzyme-catalysed reactions

Suckling, Colin J.

Journal:

Chemical Society Reviews

Year:

1984

Language:

english

File:

PDF, 1.61 MB

english, 1984

8

Die Cyclopropylgruppe in Untersuchungen über Mechanismus und Hemmung von Enzymen

Prof. Dr. Colin J. Suckling

Journal:

Angewandte Chemie

Year:

1988

Language:

german

File:

PDF, 1.51 MB

german, 1988

9

Mechanistic Principles of Enzyme Activity. Herausgegeben von J. F. Liebman und A. Greenberg. VCH Verlagsgesellschaft, Weinheim/VCH Publishers, New York 1988. 404 S., geb. DM 204.00. – ISBN 3-527-26907-X/0-89573-706-X

Colin J. Suckling

Journal:

Angewandte Chemie

Year:

1990

Language:

german

File:

PDF, 294 KB

german, 1990

10

The Cyclopropyl Group in Studies of Enzyme Mechanism and Inhibition

Prof. Colin J. Suckling

Journal:

Angewandte Chemie International Edition

Year:

1988

Language:

english

File:

PDF, 1.56 MB

english, 1988

11

Book Review: Mechanistic Principles of Enzyme Activity. Edited by J. F. Liebman and A. Greenberg

Colin J. Suckling

Journal:

Angewandte Chemie International Edition

Year:

1989

Language:

english

File:

PDF, 304 KB

english, 1989

12

Solvent effects on biocatalysis in organic systems: Equilibrium position and rates of lipase catalyzed esterification

Rao H. Valivety, Grant A. Johnston, Colin J. Suckling, Peter J. Halling

Journal:

Biotechnology and Bioengineering

Year:

1991

Language:

english

File:

PDF, 670 KB

english, 1991

13

ChemInform Abstract: Specific Inhibitors in Vitamin Biosynthesis. Part 11. Syntheses of Pterins with Extended Side Chains at C-6.

Colin L. Gibson, Angus Lang, Kyuji Ohta, Colin J. Suckling

Journal:

Year:

1999

File:

PDF, 32 KB

1999

14

ChemInform Abstract: Cholest-5-ene-3β,4β-diyl Diacetate.

Alan R. Kennedy, Andrew R. Pitt, Colin J. Suckling, Keith E. Suckling, Michael Thomas

Journal:

Year:

2000

File:

PDF, 27 KB

2000

15

ChemInform Abstract: The Synthesis of A- and B-Ring Fluorinated Analogues of Cholesterol.

Michael G. Thomas, Colin J. Suckling, Andrew R. Pitt, Keith E. Suckling

Journal:

Year:

2000

File:

PDF, 31 KB

2000

16

ChemInform Abstract: On the Specificity of Reactions Catalyzed by the Antibody H11.

Abedawn I. Khalaf, Sabin Linaza, Andrew R. Pitt, William H. Stimson, Colin J. Suckling

Journal:

Year:

2000

File:

PDF, 28 KB

2000

17

ChemInform Abstract: Synthesis of Novel DNA Binding Agents: Indole-Containing Analogues of Bis-netropsin.

Abedawn I Khalaf, Andrew R. Pitt, Martin Scobie, Colin J. Suckling, John Urwin, Roger D. Waigh, Robert V. Fishleigh, Stephen C. Young

Journal:

Year:

2000

File:

PDF, 28 KB

2000

18

ChemInform Abstract: Unexpected Dealkylation During Nucleophilic Substitution: Synthesis of 2-N,N-Dialkylamino Benzoxazoles and Benzothiazoles.

Abedawn I. Khalaf, Ricardo G. Alvarez, Colin J. Suckling, Roger D. Waigh

Journal:

Year:

2001

File:

PDF, 33 KB

2001

19

Syntheses of Highly Functionalized 6-Substituted Pteridines.

Donie Guiney, Colin L. Gibson, Colin J. Suckling

Journal:

Year:

2003

File:

PDF, 174 KB

2003

20

ChemInform Abstract: Diversity Oriented Synthesis: Substitution at C5 in Unreactive Pyrimidines by Claisen Rearrangement and Reactivity in Nucleophilic Substitution at C2 and C4 in Pteridines and Pyrido[2,3-d]pyrimidines.

Jonathan Adcock, Colin L. Gibson, Judith K. Huggan, Colin J. Suckling

Journal:

Year:

2011

Language:

english

File:

PDF, 44 KB

english, 2011

21

Comparison of DNA Complex Formation Behaviour for Two Closely Related Lexitropsin Analogues

John A. Parkinson, Abedawn I. Khalaf, Nahoum G. Anthony, Simon P. MacKay, Colin J. Suckling, Roger D. Waigh

Journal:

Helvetica Chimica Acta

Year:

2009

Language:

english

File:

PDF, 1.31 MB

english, 2009

22

Effects of novel synthetic sterol probes on enzymes of cholesterol metabolism in cell-free and cellular systems

Rachel A. Harte, Stephen J. Yeaman, John McElhinney, Colin J. Suckling, Brian Jackson, Keith E. Suckling

Journal:

Chemistry and Physics of Lipids

Year:

1996

Language:

english

File:

PDF, 1.04 MB

english, 1996

23

Pyrroles and related compounds—XXXVII : Harderoporphyrin

Anthony H. Jackson, George W. Kenner, Kevin M. Smith, Colin J. Suckling

Journal:

Year:

1976

Language:

english

File:

PDF, 627 KB

english, 1976

24

The Synthesis of Haptens and Properties of Catalytic Antibodies Designed to Catalyse Carbanionic Cyclisation Reactions

Marion Currie, Colin J. Suckling, Li-min Zhu, June Irvine, William H. Stimson

Journal:

Year:

1995

Language:

english

File:

PDF, 558 KB

english, 1995

25

Selective functionalisation. Part 5 The influence of some functional polymers upon the chlorination of phenol by tert-butyl hypochlorite

James G. Heffernan, David C. Sherrington, Colin J. Suckling

Journal:

Reactive Polymers, Ion Exchangers, Sorbents

Year:

1982

Language:

english

File:

PDF, 644 KB

english, 1982

26

A modelling study of a non-concerted hydrolytic cycloaddition reaction by the catalytic antibody H11

Rachel L. Clark, Blair F. Johnston, Colin J. Suckling, Simon P. Mackay

Journal:

Bioorganic & Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 3.17 MB

english, 2006

27

DNA binding of a short lexitropsin

Nahoum G Anthony, Keith R Fox, Blair F Johnston, Abedawn I Khalaf, Simon P Mackay, Iain S McGroarty, John A Parkinson, Graham G Skellern, Colin J Suckling, Roger D Waigh

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 344 KB

english, 2004

28

DNA sequence recognition by an imidazole-containing isopropyl-substituted thiazole polyamide (thiazotropsin B)

Andrew J. Hampshire, Hannah Khairallah, Abedawn I. Khalaf, Abdolrasoul H. Ebrahimabadi, Roger D. Waigh, Colin J. Suckling, Tom Brown, Keith R. Fox

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 348 KB

english, 2006

29

M4 agonists/5HT7 antagonists with potential as antischizophrenic drugs: Serominic compounds

Colin J. Suckling, John A. Murphy, Abedawn I. Khalaf, Sheng-ze Zhou, Dimitris E. Lizos, Albert Nguyen van Nhien, Hiroshi Yasumatsu, Allan McVie, Louise C. Young, Corinna McCraw, Peter G. Waterman, Bri

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 390 KB

english, 2007

30

6-Acetyl-7,7-dimethyl-5,6,7,8-tetrahydropterin is an activator of nitric oxide synthases

Colin J. Suckling, Colin L. Gibson, Judith K. Huggan, Raghavendar R. Morthala, Brendan Clarke, Suma Kununthur, Roger M. Wadsworth, Simon Daff, Davide Papale

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 481 KB

english, 2008

31

The synthesis of 7-deazaguanines as potential inhibitors of guanosine triphosphate cyclohydrolase I

Colin L Gibson, Salvatore La Rosa, Kyuji Ohta, Peter H Boyle, Fabien Leurquin, Alexandra Lemaçon, Colin J Suckling

Journal:

Year:

2004

Language:

english

File:

PDF, 595 KB

english, 2004

32

Diversity oriented synthesis: substitution at C5 in unreactive pyrimidines by Claisen rearrangement and reactivity in nucleophilic substitution at C2 and C4 in pteridines and pyrido[2,3-d]pyrimidines

Jonathan Adcock, Colin L. Gibson, Judith K. Huggan, Colin J. Suckling

Journal:

Year:

2011

Language:

english

File:

PDF, 871 KB

english, 2011

33

Latent inhibitors Part 10. The inhibition of carboxypeptidase a by tetrapeptide analogues based on 1-aminocyclopropane carboxylic acid

Stephen Husbands, Christopher A. Suckling, Colin J. Suckling

Journal:

Year:

1994

Language:

english

File:

PDF, 764 KB

english, 1994

34

Selective functionalisatlon: Part 10. The nitration of phenols by pyridine derivatives carrying a transferable nitro group

Humayun Pervez, Samuel O. Onyiriuka, Lilias Rees, James R. Rooney, Colin J. Suckling

Journal:

Year:

1988

Language:

english

File:

PDF, 936 KB

english, 1988

35

Asymmetric reduction of dihydrofolate using dihydrofolate reductase and chiral boron-containing compounds

Lilias Rees, Edward Valente, Colin J. Suckling, Hamish C.S. Wood

Journal:

Year:

1986

Language:

english

File:

PDF, 1.43 MB

english, 1986

36

Ring opening of oxiranylmethyl and 3-methyl-3-oxetanylmethyl radicals

David Laurie, Derek C. Nonhebel, Colin J. Suckling, John C. Walton

Journal:

Year:

1993

Language:

english

File:

PDF, 301 KB

english, 1993

37

On the Specificity of Reactions Catalysed by the Antibody H11

Abedawn I Khalaf, Sabin Linaza, Andrew R Pitt, William H Stimson, Colin J Suckling

Journal:

Year:

2000

Language:

english

File:

PDF, 250 KB

english, 2000

38

Selective hydrogenation by a novel palladium(II) complex

James M. Kerr, Colin J. Suckling, Peter Bamfield

Journal:

Tetrahedron Letters

Year:

1988

Language:

english

File:

PDF, 244 KB

english, 1988

39

Novel reactivity of 2-(chloromethoxy)ethyl acetate

David J. Aitken, Lilias Rees, Colin J. Suckling, Hamish C.S. Wood

Journal:

Tetrahedron Letters

Year:

1986

Language:

english

File:

PDF, 165 KB

english, 1986

40

5α,6α-Methanocholestan-3 β-ol as a probe of the mechanism of action of cholesterol 7α-hydroxylase

Jennifer D. Houghton, Sarah E. Beddows, Keith E. Suckling, Linda Brown, Colin J. Suckling

Journal:

Tetrahedron Letters

Year:

1986

Language:

english

File:

PDF, 232 KB

english, 1986

41

Redox reactions of pyridinium salts

Alexander Shirra, Colin J. Suckling

Journal:

Tetrahedron Letters

Year:

1975

Language:

english

File:

PDF, 99 KB

english, 1975

42

Water insoluble indicators for the measurement of pH in water immiscible solvents

Linda Brown, Peter J. Halling, Grant A. Johnston, Colin J. Suckling, Rao H. Valivety

Journal:

Tetrahedron Letters

Year:

1990

Language:

english

File:

PDF, 292 KB

english, 1990

43

A traceless solid-phase synthesis of pteridines

Colin L. Gibson, Salvatore La Rosa, Colin J. Suckling

Journal:

Tetrahedron Letters

Year:

2003

Language:

english

File:

PDF, 109 KB

english, 2003

44

An antibody with dual catalytic activity

Colin J. Suckling, M.Catriona Tedford, Laura M. Bence, June I. Irvine, William H. Stimson

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1992

Language:

english

File:

PDF, 260 KB

english, 1992

45

An unusual stable adduct in the reaction of pyruvate with papain Chemically modiied by 3-acetyl pyridinium and quinolinium derivatives

Lorraine Anderson, Colin J. Suckling, Li-Min Zhu

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 223 KB

english, 1994

46

Carbon-carbon bond formation mediated by papain chemically modified by thiazolium salts

Colin J. Suckling, Li-Min Zhu

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1993

Language:

english

File:

PDF, 250 KB

english, 1993

47

On the mechanism of action of GTP-transforming enzymes

Mark J. Dufton, Colin L. Gibson, Andrew R. Pitt, Salah Athmani, Colin J. Suckling

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 440 KB

english, 1997

48

Molecular recognition and physicochemical properties in the discovery of selective antibacterial minor groove binders

Colin J. Suckling

Journal:

Journal of Physical Organic Chemistry

Year:

2008

Language:

english

File:

PDF, 397 KB

english, 2008

49

Measurement of pH changes in an inaccessible aqueous phase during biocatalysis in organic media

Rao H. Valivety, Johannes L. L. Rakels, Rosa M. Blanco, Grant A. Johnston, Linda Brown, Colin J. Suckling, Peter J. Halling

Journal:

Biotechnology Letters

Year:

1990

Language:

english

File:

PDF, 428 KB

english, 1990

50

A fluorine-19 and deuterium NMR study of two novel fluorosterols and their properties in model membranes and high density lipoprotein

David G. Reid, Lesley K. MacLachlan, Keith E. Suckling, Andrew Gee, Susan Cresswell, Colin J. Suckling

Journal:

Chemistry and Physics of Lipids

Year:

1991

Language:

english

File:

PDF, 380 KB

english, 1991